| 1 | 1,4‐Dearomatization of Pyridines and Quinolines Enabled by the
Carbodication Lewis Acid | ACIE |
| 2 | meta ‐Hydroxylation of Pyridines,
Quinolines, and Isoquinolines Using Dearomatized Intermediates | ACIE |
| 3 | A General Strategy to Access Pharmaceutically Relevant Pyridines from
Nitroarenes | ACIE |
| 4 | A Versatile Carbonylative Approach to Ureas and Carbamates through
Light Activated Nickel Catalyzed Formation of Aliphatic Isocyanates | ACIE |
| 5 | Accelerating Medicinal Chemistry: A C(sp
3 )‐Rich Fragment Toolbox for
Redox‐Neutral Cross‐Coupling | ACIE |
| 6 | Access to Quaternary‐Substituted Cyclobutylsilanes by Ring Opening of
Arylbicyclobutanes with Silyllithium Reagents | ACIE |
| 7 | Accessing N
‐Unprotected Unnatural α‐Amino Acid Esters by Half‐Sandwich
Chiral‐at‐Ruthenium Aldehyde Catalysis: Scope and Mechanistic Study | ACIE |
| 8 | Amine‐Ligated Boryl Radicals Enables Direct C─F Borylation and
Cross‐Couplings of Polyfluoroarenes | ACIE |
| 9 | Automated Iterative N─C and C─C Bond Formation | ACIE |
| 10 | C(sp 2 )─H Bond
Activation with a Heterometallic Nickel–Aluminium Complex | ACIE |
| 11 | Catalytic Enantioselective Synthesis of Axially Chiral
Tetraarylethenes | ACIE |
| 12 | Cobalt‐Catalyzed Hydroglycosylation of Alkynes for the Synthesis of
Vinyl α ‐
C ‐Glycosides | ACIE |
| 13 | Cu(I)‐Catalyzed Enantioselective Epoxidation of Aldehydes with
α‐Trifluoromethyl Diazosilanes | ACIE |
| 14 | C─C Bond Formation via Reductive Elimination at Rare Earth Centers | ACIE |
| 15 | Deoxygenative Functionalization of Alcohols and Carbonyl Compounds via
Electrochemical Reduction | ACIE |
| 16 | Direct Asymmetric α‐Alkylation of β‐Ketocarbonyl
Compounds with Simple Olefins by Photoredox‐Nickel‐Hydrogen Atom
Transfer Triple Catalysis | ACIE |
| 17 | Effect of Alternating Polarity in Electrochemical Olefin
Hydrocarboxylation | ACIE |
| 18 | Enantioselective Acylation of Benzylic C(sp3)−H Bond
Enabled by a Cooperative Photoredox and N‐Heterocyclic Carbene
Catalysis | ACIE |
| 19 | Enantioselective Borylcupration/Cyclization of Alkene‐Tethered Oxime
Esters | ACIE |
| 20 | Enantioselective Synthesis of α‐Hydroxy Allyl Ketones via
BINAP‐CuH‐Catalyzed Hydroacylation | ACIE |
| 21 | Facile ( Z )‐Selective
Synthesis of β,γ‐Unsaturated Ketones by a Silicon‐based Olefination
Strategy | ACIE |
| 22 | Formal C─H Functionalization of Quinolines at the C7 Position Through
a Traceless Directing Strategy | ACIE |
| 23 | Frontispiece: Reductant‐Free Enantioselective Aza‐Reformatsky
Reaction Enabled by Synergistic Visible Light Photocatalysis and Lewis
Acid Catalysis | ACIE |
| 24 | Heteroatom‐Assisted Regio‐ and Stereoselective Hydrosilylation of
Unsymmetric Internal Alkynes by Scandium Catalyst | ACIE |
| 25 | High‐Valent Cobalt‐Difluoride in Oxidative Fluorination of Saturated
Hydrocarbons | ACIE |
| 26 | Homologative 1,3‐Functionalization of Alkenes via an Iodomethyl
Thianthrenium Reagent | ACIE |
| 27 | Iridium‐Catalyzed Enantioselective Formal
meta ‐Allenylation of Pyridines | ACIE |
| 28 | Isoselenourea‐Catalyzed Enantioselective Pyrazolo‐Heterocycle
Synthesis Enabled by Self‐Correcting Amide and Ester Acylation | ACIE |
| 29 | Ligand‐Enabled Nondirected and Regioselective Arylation of Internal
Alkenes with Simple Arenes | ACIE |
| 30 | Nickel‐Catalyzed Regioselective and Enantioselective Olefin–Aldehyde
Cross‐Couplings Toward Acyloin Isosteres | ACIE |
| 31 | Nitrate Reduction for Deaminative Suzuki–Miyaura Coupling of Anilines | ACIE |
| 32 | On‐Demand Nitric Oxide Generation via Thermal Decomposition of
N ‐Trityl Dihydro‐1,2‐Oxazines | ACIE |
| 33 | Oxidative Addition of Aryl Bromides at Palladium(I) to form
Palladium(III) Complexes | ACIE |
| 34 | Palladium‐Catalyzed Meta C─H Alkoxylation and Amidation via Polarity
Reversal of Nucleophilic Reagents | ACIE |
| 35 | Pd‐Catalyzed Skeletal Rearrangement via C(
sp 3 )−C(
sp 3 )
Activation to Access α
, β ‐Unsaturated
δ / γ
‐Lactone | ACIE |
| 36 | Ph 3 PC – A
Monosubstituted C(0) Atom in Its Triplet State | ACIE |
| 37 | Photochemical Conversion of Indazoles into Benzimidazoles | ACIE |
| 38 | Phototransposition of Indazoles to Benzimidazoles: Tautomer‐Dependent
Reactivity, Wavelength Dependence, and Continuous Flow Studies | ACIE |
| 39 | Photo‐Induced Catalytic Dearomative Coupling of
N ‐Heteroarenes | ACIE |
| 40 | Radical C─H‐Aroylation of Allenes via Cooperative Photoredox and
N ‐Heterocyclic Carbene Catalysis | ACIE |
| 41 | Rapid Synthesis and Diversification of Thymine‐Containing Bridged
Nucleic Acids Through Cascade Cyclization Reactions | ACIE |
| 42 | Reductant‐Free Enantioselective Aza‐Reformatsky Reaction
Enabled by Synergistic Visible Light Photocatalysis and Lewis Acid
Catalysis | ACIE |
| 43 | Regiodivergent and Enantioselective Allylic C−H Alkylation of Allyl
Ethers: Optimization, Scope, Mechanism and Application | ACIE |
| 44 | Regiodivergent and Enantioselective Hydroboration of Dienol Ethers | ACIE |
| 45 | Regio‐ and Enantioconvergent Hydroallylation of Acrylates Enabled by
γ‐Silyl‐Substituted Allyl Acetates | ACIE |
| 46 | Rhodium‐Catalyzed One‐Carbon Ring Expansion of Aziridines with
Vinyl‐N‐triftosylhydrazones for the Synthesis of 2‐Vinyl
Azetidines | ACIE |
| 47 | Ring Expansion via Palladium‐Catalyzed Aryne Insertion into C−C Bonds
of Benzocyclobutenones | ACIE |
| 48 | Selectively Deoxygenative Deuteration of Aldehydes by Superwetting
Porous Carbon‐Supported Palladium Catalysts | ACIE |
| 49 | Site‐Selective Carbonylation of Azetidines via Copper‐Catalyzed
Difluorocarbene Insertion | ACIE |
| 50 | Steady State Free Precession NMR without Fourier Transform: Redefining
the Capabilities of 19F NMR as a Discovery Tool | ACIE |
| 51 | Synthesis and Reactivity of Six‐Membered Cyclic Diaryl
λ3‐Bromanes and λ3‐Chloranes | ACIE |
| 52 | Synthesis of Thiophenes from Pyridines Using Elemental Sulfur | ACIE |
| 53 | Synthesis of α‐N‐Heteroaryl Ketones by Nickel‐Catalyzed Chemo‐, Regio‐
and Enantioselective Carbonylation of Alkenes and N‐Alkenyl
Heteroarenes | ACIE |
| 54 | Toward Iron‐Catalyzed Alkene Metathesis: Mapping the Reactivity and
Deactivation Pathways of an Iron Metallacyclobutane | ACIE |
| 55 | Transition Metal‐Free Formal C─H/C─H Coupling of Arylacetamides and
Sulfoxides: An Interrupted Pummerer/[2,3]‐sigmatropic Rearrangement
Sequence | ACIE |
| 56 | “Angular” Spirocyclic Azetidines: Synthesis, Characterization, and
Evaluation in Drug Discovery | ACIE |
| 57 | In Situ Generated Triazine Co-Catalyst
Unlocks Amidine Arylation under Dual Nickel/Photoredox Catalysis: A
Platform for Mild C–N Bond Formation | ACS Catal. |
| 58 | N , N
-Difluoroarylsulfonamides: A Reagent for Chemodivergent
Trifunctionalization of Unactivated Alkenes to Construct Quinoline
Isosteres | ACS Catal. |
| 59 | Accessing Arenes via the Hydrodeoxygenation of Phenolic Derivatives
Enabled by Hydrazine | ACS Catal. |
| 60 | Auxiliary-Directed δ-C(sp 3
)–H Functionalization Enabled by Dual Photoredox and Palladium
Catalysis | ACS Catal. |
| 61 | Bifunctional Iron Catalyst for Endoselective Cycloisomerization of
Nucleophile-Functionalized Terminal Alkynes | ACS Catal. |
| 62 | Boronic Acid Catalysis for Diol Activation under Lewis Base Promotion:
Site-Selective Propargylation of Carbohydrates | ACS Catal. |
| 63 | CPAPhosAuCl as Dual Chiral Organocatalyst and Au(I)-Complex for Relay
Catalysis: Application in the Synthesis of Chiral Indole Alkaloids | ACS Catal. |
| 64 | Catalytic Deoxygenation of Unactivated 1,2-Diol Motifs via Light-
Induced Spin-Center Shift | ACS Catal. |
| 65 | Catalytic In Situ Acetalization Strategy for High-Yield Synthesis of C
4 - and C
2 -Carbohydrate Derivatives from
Glucose | ACS Catal. |
| 66 | Cobalt-Catalyzed Markovnikov Hydrofluorocarbonylation of Unactivated
Alkenes | ACS Catal. |
| 67 | Copper-Catalyzed Intermolecular Asymmetric Transformations of Vinyl
Cations via [1,2]-Stevens-Type Rearrangement | ACS Catal. |
| 68 | Divergent Transformations of Cobaltacyclobutenes Generated from [2 +
2]-Cycloadditions of Vinylidenes and Alkynes | ACS Catal. |
| 69 | Diverse C–H Activation in Asymmetric Multicomponent Coupling:
Unlocking Anti-Parkinson Pseudo-Natural Macrocycles | ACS Catal. |
| 70 | Electronic and Steric Effects of the ProPhos Ligand Family for Nickel-
Catalyzed Suzuki–Miyaura Coupling of Heteroaromatics | ACS Catal. |
| 71 | Enhanced Electrocatalytic and Selective CO
2 -to-CO Reduction by a Rhenium(I)
Complex Bearing 6,6′-Substituted 2,2′-Bipyridines | ACS Catal. |
| 72 | Harnessing a Tripyridyl Ligand in Zirconaaziridine-Mediated Ni-
Catalyzed Cross-Electrophile Couplings | ACS Catal. |
| 73 | Initiation of Palladium Precatalysts: Efficiency and Product
Selectivity as a Function of Ligand, Substrate, and Reaction
Conditions | ACS Catal. |
| 74 | Intraporous Liquid Water Stabilizes PdCu/Zeolite Catalysts for Wacker
Oxidation of Ethylene | ACS Catal. |
| 75 | Iron-Catalyzed Ipso-Nitration of Aryl Borides via Visible-
Light-Induced β-Homolysis | ACS Catal. |
| 76 | Ligand-Enabled “Two-in-One” Metallaphotocatalytic Cross Couplings | ACS Catal. |
| 77 | Mechanistically Driven Development of Kumada Catalyst-Transfer
Polymerizations: A Rapid Injection NMR Study | ACS Catal. |
| 78 | Mn-Catalyzed Regio- and Stereoselective C(sp3)–H
Lactonization of Carboxylic Acids with H2O2 | ACS Catal. |
| 79 | Origin of Chemoselectivity Associated with
N -Heterocyclic Carbenes as C1 Synthons
versus Organocatalysts | ACS Catal. |
| 80 | Regio- and Enantioselective Palladium-Catalyzed (4 + 2)
Silacycloaddition of Unsymmetrical Internal Alkynes with Racemic
Benzosilacyclobutenes | ACS Catal. |
| 81 | Regio- and Enantioselective Pictet–Spengler Reaction of α-Diketones
Catalyzed by a Single H-Bond Donor Organocatalyst | ACS Catal. |
| 82 | Rh 2 (II)-Catalyzed
Asymmetric Si–H Insertion of α-Alkyl-Donor Carbene from Diynes:
Constructing C/Si-Stereocenters by Outcompeting β-H Migration | ACS Catal. |
| 83 | Site-Selective Defluorinative Functionalization of Unactivated Alkenes
Enabled by Cobalt/Photoredox Relay Catalysis | ACS Catal. |
| 84 | Stereoselective Radical Cross-Coupling of Amino Acids and Imines via
Hydrogen-Bond Catalysis | ACS Catal. |
| 85 | Sulfonylation of Anilines through Photocatalytic Activation of
N -Hydroxymethylphthalimide Sulfones | ACS Catal. |
| 86 | The Multiple Roles of Bipyridine-Nickel(II) Complex in Versatile
Photoredox C(sp2)–C(sp3) Cross-Coupling | ACS Catal. |
| 87 | Titanocene-Catalyzed Hydrosilylation of Oxetanes─are Oxetanes the
Better Epoxides? | ACS Catal. |
| 88 | Unveiling the Origins of Enantioconvergence in Cobalt-Catalyzed
Asymmetric Hydrogenation of Minimally Functionalized Isomeric Olefins | ACS Catal. |
| 89 | Heterocyclic Assembly: An Underutilized Disconnection with Potential
to Maximize High Fsp3 Chemical Space Exploration | ACS Med. Chem. Lett. |
| 90 | Short and High-Yielding Synthesis of a Minimalist Diazirine–Alkyne
Photo-Cross-Linker and Photoaffinity Labeling Derivatives | ACS Omega |
| 91 | Benzestrol Isomer Stereochemistry Determines the Distinct Estrogenic
Activities and Conformations of the Eight Isomers When Bound to
Estrogen Receptor α | ACS Pharm. Trans. Sci. |
| 92 | Dicobalt-catalyzed N=N coupling reactions of tertiary alkyl azides to
form azoalkanes | Chem |
| 93 | Photocatalytic hydrogenation of alkenes using ammonia-borane | Chem |
| 94 | Radical sorting as a general framework for deaminative C(sp3)–C(sp2)
cross-coupling | Chem |
| 95 | A Tetrazine‐Based Synthesis for Accessing Underutilized Aza‐Indole
Analogues | Chem. Eur. J. |
| 96 | Chiral iron porphyrin (+)-D4-(por)FeCl catalyzes highly
enantioselective cyclopropanation of alkenes using in situ
generated diazoacetonitrile with up to 35 000 product turnover | Chem. Sci. |
| 97 | Copper-catalyzed direct regioselective C5–H alkylation reactions of
functionalized indoles with α-diazomalonates | Chem. Sci. |
| 98 | Design, modular synthesis and screening of 58 shape-diverse 3-D
fragments | Chem. Sci. |
| 99 | Difluoroenol phosphinates as difluoroenolate surrogates: synthesis and
applications in defluorination and deoxygenative coupling | Chem. Sci. |
| 100 | Recommending reaction conditions with label ranking | Chem. Sci. |
| 101 | A comparative HS-SPME-GC–MS-based volatile fingerprint analysis of
newly developed milk beverages fermented with autochthonous and
commercial cultures | Food Chemistry |
| 102 | A Stable Chromium(III) Catalyst for Ring-Opening Alternating
Copolymerization of Cyclic Anhydrides/Epoxides under Air | Inorg. Chem. |
| 103 | Hydrolytic Cleavage and Deborylation of Boron(III)
Subphthalocyanines─A Synthetic Approach to Fused Diazatripyrrins | Inorg. Chem. |
| 104 | (Salen)Metal-Catalyzed β-Glucuronidation of Alcohols, Phenols, and
Anilines | JACS |
| 105 | In Crystallo Wolff Rearrangement of a Metalated Diazoester:
Structural Confirmation of the Singlet Carbene Wolff-Intermediate | JACS |
| 106 | Remote-Markovnikov Hydrobromination and Hydrochlorination of
Allyl Carboxylates via Dual Photoredox/Cobalt Catalysis | JACS |
| 107 | anti -Diastereo- and Enantioselective
Ruthenium-Catalyzed C–C Coupling-Oxidative Lactonization of
1,4-Butanediol: Alkynes as Allylmetal Pronucleophiles | JACS |
| 108 | A 100,000-Fold Increase in C–H Bond Acidity Gives Palladium a Key
Advantage in C(sp 3
)–H Activation Compared to Nickel | JACS |
| 109 | A Catalysis-Driven Dual Molecular Motor | JACS |
| 110 | A Catalytic Asymmetric Intramolecular [4 + 1]-Cycloaddition for the
Total Synthesis of Terpene Alkaloid Natural Products | JACS |
| 111 | A Concise Total Synthesis of Glycinoeclepin A | JACS |
| 112 | A Data Science-Guided Approach for the Development of Nickel-Catalyzed
Homo-Diels–Alder Reactions | JACS |
| 113 | A General Copper-Catalyzed Radical Cross-Coupling of Unactivated Alkyl
Halides | JACS |
| 114 | A General Three-Component Nozaki–Hiyama–Kishi-Type Reaction Enabled by
Delayed Radical-Polar Crossover | JACS |
| 115 | A Ring-Deconstructive Carbon-Deletion Approach to the Enantioselective
Total Synthesis of [5]-Ladderanoic Acid | JACS |
| 116 | A Tailored Quinoline-Locked Covalent Organic Framework for Metal-Free
Photocatalytic α-Amino C–H Annulation | JACS |
| 117 | Alkene Borylation–Hydrogenation Enables Highly Active, Site-Selective
Cobalt-Catalyzed Borylation | JACS |
| 118 | Alkyl Fluoride Synthesis via Cu-Mediated Deacetylative Fluorination | JACS |
| 119 | Aminoalkylation of Alkenes Enabled by Triple Radical Sorting | JACS |
| 120 | An ECEC Mechanism via an Electrophilic Co(II) Carbene in Reductive
Cyclopropanation | JACS |
| 121 | Application of Asymmetric Catalysis in the
E / Z
-Stereodivergent Synthesis of Alkenes | JACS |
| 122 | Applying Active Learning toward Building a Generalizable Model for Ni-
Photoredox Cross-Electrophile Coupling of Aryl and Alkyl Bromides | JACS |
| 123 | Aryl Acid-Alcohol Cross-Coupling: C(sp3)–C(sp2)
Bond Formation from Nontraditional Precursors | JACS |
| 124 | Asymmetric C–H Amination via Fe(III)-Metalloradical Catalysis
Featuring α-Fe(IV)-Aminyl Radicals as Key Intermediates | JACS |
| 125 | Asymmetric C–H Functionalization of
N-Boc-2,5-dihydro-1H-pyrrole and Its Application as a
Key Step in the Synthesis of (−)-Dragocin D | JACS |
| 126 | Asymmetric Radical Cyclopropanation of α,β-Unsaturated Amides with
α-Boryl and α-Silyl Dibromomethanes via Cr(II)-Based Metalloradical
Catalysis | JACS |
| 127 | Asymmetric Relay Catalysis Enables Unreactive Allylic Alcohols to
Participate in 1,3-Dipolar Cycloaddition of Azomethine Ylides | JACS |
| 128 | Atomically Precise Copper Cluster for Highly Chemoselective Carbenoid
Insertion into the N–H Bond of Aliphatic Amine | JACS |
| 129 | Attractive Noncovalent Interactions versus Steric Confinement in
Asymmetric Supramolecular Catalysis | JACS |
| 130 | Automated Flow Synthesis of Artificial Heme Enzymes for
Enantiodivergent Biocatalysis | JACS |
| 131 | Bio-inspired Deconjugative Isomerization of Borylated Dienoates | JACS |
| 132 | Boraporphyrins: Unlocking Global Aromaticity in Organoboron
Macrocycles | JACS |
| 133 | Borrowing Hydrogen/Chiral Enamine Relay Catalysis Enables Diastereo-
and Enantioselective β-C–H Functionalization of Alcohols | JACS |
| 134 | Bro̷nsted Acid-Catalyzed Reduction of Furans | JACS |
| 135 | C(sp3)H/N(sp2) Cross-Coupling Reaction for the
Synthesis of Tertiary Arylamines via Fluxional SOX·Pd(II) Catalysis | JACS |
| 136 | C2-Selective Palladium-Catalyzed C–S Cross-Coupling of
2,4-Dihalopyrimidines | JACS |
| 137 | Cage Alkyl Carbenes Provide Experimental Evidence for Isotope-
Controlled Selectivity in Competing Tunneling Reactions | JACS |
| 138 | Can the Hock Process Be Used to Produce Phenol from Polystyrene? | JACS |
| 139 | Carbene Reactivity Directly from Aldehydes via Low-Valent Iron
Electrocatalysis | JACS |
| 140 | Carbon-Atom Scavengers Enable Divergent, Selective Carbon Deletion of
Azaarenes | JACS |
| 141 | Catalyst-Controlled Site-Selective and Epimer-Selective Hydrogenations
of Thiostrepton | JACS |
| 142 | Catalytic Asymmetric Synthesis of Axially Chiral
Methylenecyclopropanes | JACS |
| 143 | Catalytic Enantioselective Synthesis of 1,4-(Hetero) Dicarbonyl
Compounds through α-Carbonyl Umpolung | JACS |
| 144 | Catalytic Enantioselective α-Fluorination of Ketones with CsF | JACS |
| 145 | Catalytic Metalloradical System for Radical 1,6-C(sp3)–H
Amination with Concurrent Control of Site-, Chemo-, and Enantio-
selectivity | JACS |
| 146 | Catalytic Regio- and Enantioselective Hydroformylation of
Trisubstituted Alkenes to Construct α-Quaternary Lactams | JACS |
| 147 | Chemoselective Electrochemical Coupling of Thioethers and Primary
Amines for Accessing Sulfilimines and Sulfoximines | JACS |
| 148 | Chiral Hydrogen-Bond Donor and Gold(I) Cocatalysis Enables
Enantioselective Dearomative Spirocyclization of Naphthols | JACS |
| 149 | Chiral Primary Amine-Catalyzed Asymmetric Photochemical Reactions of
Pyridotriazoles with Boronic Acids to Access Triarylmethanes | JACS |
| 150 | Cobalt-Catalyzed Enantioconvergent Decarboxylative N-Alkylation | JACS |
| 151 | Concise Syntheses of Lycojapomine Alkaloids Enabled by Radical
Dearomatization of a Pyrrole | JACS |
| 152 | Concise Synthesis of Fostriecin and Analogs through Late-Stage
Chemoenzymatic Installation of Their Key Pharmacophores | JACS |
| 153 | Cooperative Heterobimetallic CO2 Activation Involving a
Mononuclear Aluminum(II) Intermediate | JACS |
| 154 | Copper-Catalyzed Enantioselective Synthesis of
N -Heterocycle-Substituted Quaternary
Carbon Stereogenic Centers | JACS |
| 155 | Copper-Catalyzed Formal Aldehydic C–H Borylation Enabled by an
sp2–sp3 Diboron Reagent | JACS |
| 156 | Cross-Electrophile Coupling of Aryl Chlorides with Alkyl Chlorides
Using Rotating Magnetic Field and Metal Rods | JACS |
| 157 | Cross-Electrophile Coupling to Form Sterically Hindered
C(sp2)–C(sp3) Bonds: Ni and Co Afford
Complementary Reactivity | JACS |
| 158 | Cu-Catalyzed Diastereo- and Enantioselective Synthesis of Borylated
Cyclopropanes with Three Contiguous Stereocenters | JACS |
| 159 | Cu-Catalyzed Enantioselective Carbene Insertion into Ge–H and Si–H
Bonds Enabled by SPSiBox with a Tunable Chiral Pocket | JACS |
| 160 | C–C Bond Cleavage in the Late-Stage Biosynthesis of Huperzine
Alkaloids Occurs via Enzymatic Retro-Aza-Prins Reaction | JACS |
| 161 | C–C Cleavage/Cross-Coupling Approach for the Modular Synthesis of
Medium-to-Large Sized Rings: Total Synthesis of Resorcylic Acid
Lactone Natural Products | JACS |
| 162 | C–H Functionalization via Single Atom Metathesis of C–H and C–X Bonds | JACS |
| 163 | Data Science-Guided Development of Deoxyfluorination Reagents with
Enhanced Reactivity, Practicality, and Safety | JACS |
| 164 | Dearomative Addition-Hydrogen Autotransfer for Branch-Selective
N-Heteroaryl C–H Functionalization via Ruthenium-Catalyzed C–C
Couplings of Diene Pronucleophiles | JACS |
| 165 | Dearomative Skeletal Editing of Benzenoids via Diradical | JACS |
| 166 | Defluorinative Coupling of (NH)-Heteroarenes and Unactivated Vinyl
Fluorides Enabled by Metal–Organic Frameworks | JACS |
| 167 | Dehomologative C–C Borylation of Aldehydes and Alcohols via a Rh-
Catalyzed Dehydroformylation–Borylation Relay | JACS |
| 168 | Designing Target-specific Data Sets for Regioselectivity Predictions
on Complex Substrates | JACS |
| 169 | Developing Pharmaceutically Relevant Pd-Catalyzed C–N Coupling
Reactivity Models Leveraging High-Throughput Experimentation | JACS |
| 170 | Dicationic Boron Derivatives of Schlenk’s and Thiele’s Hydrocarbon | JACS |
| 171 | Direct Deaminative Halogenation at Hindered Tertiary Centers | JACS |
| 172 | Direct-to-Biology Enabled Molecular Glue Discovery | JACS |
| 173 | Directed Evolution of Class I Aldolases for Cooperative
Photobiocatalytic Enantioselective Radical α-Alkylation of Aldehydes | JACS |
| 174 | Dirhodium–Palladium Dual-Catalyzed [1 + 1 + 3] Annulation to
Heterocycles Using Primary Amines or H2O as the Heteroatom
Sources | JACS |
| 175 | Diversity-Oriented C–H Activation Reactions of the Naphthalene
Scaffold | JACS |
| 176 | Dynamic Kinetic Asymmetric Hydroacylation: Racemization by Soft
Enolization | JACS |
| 177 | Efficient Aminations of Aryl Halides by a Cu(II) Catalyst | JACS |
| 178 | Electrochemical Single-Carbon Insertion via Distonic Radical Cation
Intermediates | JACS |
| 179 | Electronic Activation Enables the Borylation of Alkyl C–H Bonds in
Saturated Nitrogen Heterocycles | JACS |
| 180 | Elementary Steps in Olefin Metathesis: Nickelacyclobutanes via
Cycloaddition to Nickel Carbenes | JACS |
| 181 | Empowering Diastereoselective Cyclopropanation of Unactivated Alkenes
with Sulfur Ylides through Nucleopalladation | JACS |
| 182 | Enantiocontrolled Azetidine Library Synthesis via Strain-Release
Functionalization of 1-Azabicyclobutanes | JACS |
| 183 | Enantiocontrolled Cyclization to Form Chiral 7- and 8-Membered Rings
Unified by the Same Catalyst Operating with Different Mechanisms | JACS |
| 184 | Enantioconvergent Chan–Lam Coupling: Synthesis of Chiral Benzylic
Amides via Cu-Catalyzed Deborylative Amidation | JACS |
| 185 | Enantioconvergent Radical–Radical Cross-Coupling via Magnesium-
Mediated Charge-Transfer Photocatalysis | JACS |
| 186 | Enantioselective Alkylation of Primary C(sp3)–H
Bonds in N-Methyl Tertiary Amine Enabled by Iridium Complex of
Axially Chiral β-Aryl Porphyrins | JACS |
| 187 | Enantioselective Alkyl–Acyl Radical Cross-Coupling Enabled by
Metallaphotoredox Catalysis | JACS |
| 188 | Enantioselective Assembly of (Hetero)aryl Alkyl Sulfilimines via
Copper-Catalyzed S-Arylation of S-Alkyl Sulfenamides
with (Hetero)aryl Iodides | JACS |
| 189 | Enantioselective Cobalt(III)-Catalyzed [4 + 1] Annulation of
Benzamides: Cyclopropenes as One-Carbon Synthons | JACS |
| 190 | Enantioselective Radical–Radical Cross-Couplings of β-Hydroxy Amides
and N-Hydroxyphthalimide Esters via Ni/Photoredox Catalysis | JACS |
| 191 | Enantioselective Synthesis of (+)-Auriculatol A | JACS |
| 192 | Enantioselective Synthesis of Spirocyclic Nitrogen-Containing
Heterocycles Catalyzed by an Iridium-Containing Cytochrome | JACS |
| 193 | Enantioselective Synthesis of α-Oxygenated Ketones via Organocatalytic
Formal O–H Bond Insertion of Sulfonium Ylides | JACS |
| 194 | Enantioselective β-C(sp 3
)–H Nucleophilic Tosylation of Native Amides: A Synthetic Platform for
Chiral Methyl Stereocenters | JACS |
| 195 | Enzymatic Stereodivergent Synthesis of Azaspiro[2.y]alkanes | JACS |
| 196 | Experimental Mechanistic Studies on Alternating Polarity Electrolysis
for Carbon-Centered Radical Generation | JACS |
| 197 | Facile Synthesis of Housanes by an Unexpected Strategy | JACS |
| 198 | Formally Stereoretentive SN1 Reactions of Homoallylic
Tertiary Alcohols Via Nonclassical Carbocation | JACS |
| 199 | Formyl Radical Generation from Methane Oxidation Promoted by the
Superoxide Radical in Tungsten Oxide Cations
WO4+ | JACS |
| 200 | From Radical Coupling to Enantioselective Controlled Protonation:
Advancing Precise Construction of Stereocenters | JACS |
| 201 | From Structure to Function: Designing Iridium Catalysts with Spin-
Forbidden Excitation for Low-Energy Light-Driven Reactions | JACS |
| 202 | General Light-Induced Pd-Catalyzed Allylic C–H Alkylation of Internal
Alkenes: Direct Access to Tertiary and Quaternary Carbon Centers | JACS |
| 203 | General Modular and Convergent Approach to Diversely Functionalized
Allylic Systems | JACS |
| 204 | Highly Selective Carbonylation of Olefins Using CO2 and
H2 | JACS |
| 205 | Hydrogen-Mediated Reductive Cross-Coupling of Aryl Iodides with
Activated Aryl and Heteroaryl Bromides | JACS |
| 206 | Intramolecular N–O Bond Formation for the Synthesis of N-Alkyl
and N-Aryl Isoxazolidines | JACS |
| 207 | Investigating Reactivity and Selectivity in a Palladium-Catalyzed
Heteroleptic Ligand System for Electrophilic Arene Fluorination | JACS |
| 208 | Involving Carbene or Not? Mechanism of Corey–Winter Reaction | JACS |
| 209 | Iridium Polypyridyl Carboxylates as Excited-State PCET Catalysts for
the Functionalization of Unactivated C–H Bonds | JACS |
| 210 | Iridium-Catalyzed Stereocontrolled C(sp3)–C(sp3)
Cross-Coupling of Boronic Esters and Allylic Carbonates Enabled by
Boron-to-Zinc Transmetalation | JACS |
| 211 | Iridium-Catalyzed, Regio- and Stereoselective Silylation of Primary
and Secondary C( sp
3 )–H Bonds in Primary Amines | JACS |
| 212 | Iron(III)-Mediated C–H Alkylation: One-Electron Differentiation
Increases Activity and Chemoselectivity | JACS |
| 213 | Iron-Mediated Nitrate Reduction at Ambient Temperature for Deaminative
Sulfonylation and Fluorination of Anilines | JACS |
| 214 | Ketenimines as Aza-Dienophiles | JACS |
| 215 | Kharasch-Type Haloalkylation of Alkenes by Photoinduced Copper
Catalysis | JACS |
| 216 | Late-Stage Aromatic C–H Bond Functionalization for
Cysteine/Selenocysteine Bioconjugation | JACS |
| 217 | Late-Stage Photoredox-Catalyzed Aryl C–H Bond Diazomethylation with
Atomic Carbon Reagents | JACS |
| 218 | Leveraging Data Science to Elucidate Ligand Features for Pd-Catalyzed
Enantioretentive N-Arylations of Cyclic α-Substituted Amines in
Aqueous Media | JACS |
| 219 | Ligand Design Enables the Palladium-Catalyzed Intermolecular
Carbochlorocarbonylation of Alkynes and Cyclopentenone Formation | JACS |
| 220 | Ligand Evolution-Enabled Enantioselective C(sp
3 )–H Azidation | JACS |
| 221 | Ligand-Enabled Selective Coupling of MIDA Boronates to Dehydroalanine-
Containing Peptides and Proteins | JACS |
| 222 | Light-Driven Crystallization-Induced Dynamic Resolution of Amines | JACS |
| 223 | Light-Promoted C(sp 3
)–C(sp 3 )
Reductive Elimination from Dialkyl Ni
II Complexes | JACS |
| 224 | Local Electric Fields Originate Unusual Kinetic Isotope Effects in the
Hydrogen Abstraction Reactions of the Functionally Analogous P450 and
TauD Enzymes | JACS |
| 225 | Mechanisms and Synthetic Applications of Cyclic, Nonstabilized
Isodiazenes: Nitrogen-Atom Insertion into Pyrrolidines and Related
Rearrangements | JACS |
| 226 | Mechanistic Elucidation and Stereochemical Consequences of Alternative
Binding of Alkenyl Substrates by Engineered Arylmalonate Decarboxylase | JACS |
| 227 | Microcrystal Electron Diffraction-Guided Discovery of Fungal
Metabolites | JACS |
| 228 | Migrating Group Strategy for Remote Functionalization of Seven-
Membered Rings | JACS |
| 229 | Modular One-Pot Access to Boron-Carboxylated Dipyrromethene Dyes as
Visible-Light and Two-Photon Activatable Photocages | JACS |
| 230 | Modular Synthetic Platform for the Elaboration of Fragments in Three
Dimensions for Fragment-Based Drug Discovery | JACS |
| 231 | Ni-Catalyzed Enantioselective Desymmetrization: Development of
Divergent Acyl and Decarbonylative Cross-Coupling Reactions | JACS |
| 232 | Ni-Catalyzed Reductive Ring Contraction via Desulfurative Cross-
Coupling | JACS |
| 233 | Nickel-Catalyzed Asymmetric Homobenzylic Hydroamidation of Aryl
Alkenes to Access Chiral β-Arylamides | JACS |
| 234 | Nickel-Catalyzed Branched Hydroalkylation of Alkenes with Diazo
Compounds | JACS |
| 235 | Nickel-Catalyzed Cross-Electrophile Coupling of Aryl Triflates with
Alkyl Halides: Mechanism-Informed Design of More General Conditions | JACS |
| 236 | Nickel-Mediated Radical Capture: Evidence for a Concerted Inner-Sphere
Mechanism | JACS |
| 237 | Nucleophilic α- and β-Additions Enable Redox-Neutral Aziridination of
Conjugated Hydroxamates | JACS |
| 238 | Nucleophilic α-Functionalization of Benzyl Amines Using an Engineered
Threonine Aldolase | JACS |
| 239 | One-Pot Multisubstrate Screening for Asymmetric Catalysis Enabled by
19F NMR-Based Simultaneous Chiral Analysis | JACS |
| 240 | Open-Shell Species Enabled Diverse Deoxygenative
Cyanofunctionalization of Aldehydes under Metal-Free Conditions | JACS |
| 241 | Overcoming Synthetic Challenges: Solvent-Free Construction of a
Cr–Phosphonate Framework with High Stability and Proton Conductivity | JACS |
| 242 | Overriding Norrish Type II to Access Cyclopropanols | JACS |
| 243 | Palladium Bisphosphine Monoxide Complexes: Synthesis, Scope,
Mechanism, and Catalytic Relevance | JACS |
| 244 | Palladium-Catalyzed Asymmetric Hydrogenolysis of Epoxides | JACS |
| 245 | Palladium-Catalyzed Enantioselective Stereodivergent Desymmetrization
of Cyclic 1,4-Allyldiboronates | JACS |
| 246 | Palladium-Catalyzed Methylene β-C–H Fluorination of Native Amides | JACS |
| 247 | Pathway to P(V)-Stereogenic Phosphoramidates by Enantioselective
Yttrium Catalysis | JACS |
| 248 | Pd-Catalyzed Photoinduced Interceptive Decarboxylative Allylation | JACS |
| 249 | Performance-Enhancing Asymmetric Catalysis Driven by Achiral
Counterion Design | JACS |
| 250 | Pericyclic Umpolung in a Catalytic Asymmetric Diels–Alder Reaction of
Tropone with Enol Ethers | JACS |
| 251 | Persistent Boryl Radicals as Highly Reducing Photoredox Catalysts for
Debrominative Borylations | JACS |
| 252 | Photoactivated Multivariate Metal–Organic Frameworks for On-Demand
Drug Release: The Role of Host–Guest Interactions | JACS |
| 253 | Photobiocatalytic Enantioselective Benzylic C(sp3)–H
Acylation Enabled by Thiamine-Dependent Enzymes via Intermolecular
Hydrogen Atom Transfer | JACS |
| 254 | Photocatalyst-Dependent Enantioselectivity in the Light-Driven
Deracemization of Cyclic α-Aryl Ketones | JACS |
| 255 | Photocatalytic Synthesis of Substituted 2-Aryl Morpholines via
Diastereoselective Annulation | JACS |
| 256 | Photoinduced, Copper-Catalyzed Enantioconvergent Azidation of Alkyl
Halides | JACS |
| 257 | Polycyclic Scaffolds through the Intermediacy of Boron-Stabilized
Nonclassical Carbocations | JACS |
| 258 | Practical Ligand-Enabled C–H Halogenation of (Hetero)Benzoic and
(Hetero)Aryl Acetic Acids | JACS |
| 259 | Probing the Oxidative Addition Transition State in Nickel
Metallaphotoredox Catalysis Using Intramolecular 13C
Kinetic Isotope Effects | JACS |
| 260 | Profiling of Diverse Pyridoxal-5′-Phosphate Dependent Enzymes Reveals
Promiscuous Aldolase Activity with (2-Azaaryl)methanamines | JACS |
| 261 | Quantitative Determination of Electronic Effects in Free Radicals
through Open-Shell Hammett Substituent Constants | JACS |
| 262 | Radical Sorting Catalysis via Bimolecular Homolytic Substitution
(SH2): Opportunities for
C(sp3)–C(sp3) Cross-Coupling Reactions | JACS |
| 263 | Radical Strategy to the Boron-to-Copper Transmetalation Problem:
N-Alkylation with Alkylboronic Esters | JACS |
| 264 | Rapid Oxygen Atom Transfer at a Catalysis-Relevant Ni(I)–Alkyl Complex
with N2O | JACS |
| 265 | Rational Design Principles for De Novo α-Helical Peptide
Barrels with Dynamic Conductive Channels | JACS |
| 266 | Reconstitution of [Fe]-Hydrogenase with Model Complexes Reveals
Functional Roles of Methyl Groups in the Metallocofactor | JACS |
| 267 | Reductive Cyclopropanation through Bismuth Photocatalysis | JACS |
| 268 | Reductively Induced Aryl Transmetalation: An Alternative Catalytically
Relevant Ni-Catalyzed Biaryl Coupling Mechanism | JACS |
| 269 | Regiodivergent Alkylation of Pyridines: Alkyllithium Clusters Direct
Chemical Reactivity | JACS |
| 270 | Regiodivergent α- and β-Functionalization of Saturated
N-Heterocycles by Photocatalytic Oxidation | JACS |
| 271 | Regioselective Hydroamidation of α,β-Unsaturated Esters Enabled by
Lewis Acid/Iron Relay Catalysis | JACS |
| 272 | Rh(II) and Chiral Phosphoric Acid Co-catalyzed Selective O–H
Insertions for Stereodivergent O-Alkylation of Glycosides | JACS |
| 273 | Rh-Catalyzed Atroposelective Single-Carbon Insertion | JACS |
| 274 | Ring Expansions of 1,2-Amino Alcohols to Amine Heterocycles Enabled by
Proton-Coupled Electron Transfer | JACS |
| 275 | Selective C–H Borylation of Polyaromatic Compounds Enabled by Metal-
Arene π-Complexation | JACS |
| 276 | Selective Electrochemical C–N Coupling via Synergetic Chemical and
Electrochemical Microenvironment Regulation Strategies | JACS |
| 277 | Selective Ni-Catalyzed Cross-Electrophile Coupling of Heteroaryl
Chlorides and Aryl Bromides at 1:1 Substrate Ratio | JACS |
| 278 | Shake-Down Spectroscopy as State- and Site-Specific Probe of Ultrafast
Chemical Dynamics | JACS |
| 279 | Site-Selective Copper(I)-Catalyzed Hydrogenation of Amides | JACS |
| 280 | Small Molecule Catalyst for Peptide Synthesis | JACS |
| 281 | Standardized Approach for Diversification of Complex Small Molecules
via Aryl Thianthrenium Salts | JACS |
| 282 | Stereodivergent Four-Component Reactions via Rh-Carbynoids | JACS |
| 283 | Stereoselective Chemoenzymatic Cascades for the Synthesis of Densely
Functionalized Iminosugars | JACS |
| 284 | Sterically Induced Acceleration of Aryl Halide Activation by Pd(0): A
Radical Alternative to 2-Electron Oxidative Addition | JACS |
| 285 | Sulfenylcarbene-Mediated Carbon Atom Insertion for the Late-Stage
Functionalization of N-Heterocycles | JACS |
| 286 | Synthesis of 1,n-Diamines via Selective Catalytic C–H
Diamination | JACS |
| 287 | Synthesis of Bicyclo[2.1.0]pentanes and Vinylcyclopropanes Using
Palladium Carbenes: Ligand-Controlled Carbene Reactivity | JACS |
| 288 | Synthesis of Chiral Saturated Heterocycles Bearing Quaternary Centers
via Enantioselective β-C(sp3)–H Activation of Lactams | JACS |
| 289 | Synthesis of Highly Substituted Alkenes from Terminal Alkynes | JACS |
| 290 | Synthesis of a Stable Tricobalt Carbide Cluster | JACS |
| 291 | The Overlooked Stereoisomers of the Ionizable Lipid ALC315 | JACS |
| 292 | Three-Coordinate Iron(0) Complex-Catalyzed Regioselective C–H
Alkylation of Indole Derivatives | JACS |
| 293 | Total Synthesis of (−)-Illisimonin A Enabled by Pattern Recognition
and Olefin Transposition | JACS |
| 294 | Total Synthesis of (−)-Neocucurbol C Enabled by Pattern Recognition
and MHAT Cyclization | JACS |
| 295 | Total Synthesis of Enlicitide Decanoate | JACS |
| 296 | Total Synthesis of the Nominal Structure of (+)-Talaromyolide D | JACS |
| 297 | Transformation of Pyridines into 2D and 3D Fused Bicyclic Heterocycles | JACS |
| 298 | Transition-Metal-Free Site-Selective β- and γ-C–H Borylation of
Aliphatic Amines | JACS |
| 299 | Triphenylphosphine Oxide-Derived Anolyte for Application in Nonaqueous
Redox Flow Battery | JACS |
| 300 | Tungsten-Enabled Diels–Alder Cycloaddition and Cycloreversion of
Arenes and Alkynes: Divergent Synthesis of Highly Functionalized
Barrelenes and Arenes | JACS |
| 301 | Unlocking Chromium Decarboxylative Ligand-to-Metal Charge Transfer:
Efficient and Redox-Neutral Allylation of Aldehydes Using Carboxylic
Acids | JACS |
| 302 | Unlocking Epoxide Radical Anion Reactivity for Asymmetric Cross-
Coupling by Copper Metallaphotoredox | JACS |
| 303 | Unraveling the Dichotomy Exerted by Boron Reagents in Site-Selective
Functionalization of C(sp2)– and C(sp3)–OMe
Bonds | JACS |
| 304 | Vanadium-Mediated Carbon Isotope Exchange of Terminal Alkenes | JACS |
| 305 | Versatile Butenolide Syntheses via a Structure-Oriented C–H Activation
Reaction | JACS |
| 306 | Visible Light-Promoted Deracemization of α-Amino Aldehyde by
Synergistic Chiral Primary Amine and Hypervalent Iodine Catalysis | JACS |
| 307 | Visible-Light-Driven Methanol-To-Ethanol Conversion via Carbene
Pathway by Frustrated Lewis Pairs | JACS |
| 308 | β-Substituted Styrenes in Heteroaryl-Directed Hydroalkylative Cross-
Couplings: Regio-, Diastereo-, and Enantioselective Formation of
β-Stereogenic Tertiary Alcohols | JACS |
| 309 | μMap-FFPE: A High-Resolution Protein Proximity Labeling Platform for
Formalin-Fixed Paraffin-Embedded Tissue Samples | JACS |
| 310 | Two-Step Constitutional Isomerization of Saturated Cyclic Amines Using
Borane Catalysis | JACS Au |
| 311 | Brønsted Acid-Catalyzed C–H Cleavage of Alkenes: Regioselective Access
to α-Vinyl, α-Alkynyl Amino Acids | JOC |
| 312 | Catalyst-Controlled, Regiodivergent Aminooxygenation Reactions of
Dienes | JOC |
| 313 | Cobalt-Catalyzed Amide Bond Formation from Esters and Amines | JOC |
| 314 | NIS-Mediated Hofmann-Type Rearrangement to Acyl Isocyanates: A Novel
Approach for N-Acylurea Synthesis | JOC |
| 315 | Regiodivergent Switchable N1- and C3-Alkylation of Indoles with
Grignard Reagents Based on Umpolung Strategy | JOC |
| 316 | Salicylide Phenyl Oxazoline Diamine (SPODA) Ligand for Homogeneous
Cobalt-Catalyzed Deoxygenation of Sulfoxides to Sulfides | JOC |
| 317 | Samarium Diiodide/Samarium-Promoted Deoxygenative Dimerization of
Unactivated Aldehydes and Ketones to Construct Internal Alkenes via
C═O Bond Cleavage | JOC |
| 318 | Shapeshifting Gabriel Amine Synthesis with Iodo-BCPs | JOC |
| 319 | Solvent Effects in Boronic Acid-Diol Binding | JOC |
| 320 | Solventless Catalytic C–H and C–X Functionalization without Ball
Milling | JOC |
| 321 | A modular synthesis of azetidines from reactive triplet imine
intermediates using an intermolecular aza Paternò–Büchi reaction | Nat. Cat. |
| 322 | Asymmetric Hofmann–Löffler–Freytag-type reaction via a transient
carbenium ion complex merging organocatalysis and photocatalysis | Nat. Cat. |
| 323 | Enantioselective C–H annulations enabled by either nickel- or cobalt-
electrocatalysed C–H activation for catalyst-controlled
chemodivergence | Nat. Cat. |
| 324 | Enantioselective Pd-catalysed nucleophilic C(sp3)–H
(radio)fluorination | Nat. Cat. |
| 325 | Iminium catalysis in natural Diels–Alderase | Nat. Cat. |
| 326 | Site-selective Ru-catalysed saturation of unactivated arenes via
directed 6π activation | Nat. Cat. |
| 327 | A glycan foldamer that uses carbohydrate–aromatic interactions to
perform catalysis | Nat. Chem. |
| 328 | Accessing sulfonamides via formal SO2 insertion into C–N bonds | Nat. Chem. |
| 329 | Aryl halide cross-coupling via formate-mediated transfer hydrogenation | Nat. Chem. |
| 330 | Biomimetic 1,2-amino migration via photoredox catalysis | Nat. Chem. |
| 331 | Carbon-to-nitrogen atom swap enables direct access to benzimidazoles
from drug-like indoles | Nat. Chem. |
| 332 | Catalytic C(sp2) homologation of alkylboranes | Nat. Chem. |
| 333 | Catalytic difluorocarbene insertion enables access to fluorinated
oxetane isosteres | Nat. Chem. |
| 334 | Construction of sulfur stereocentres by asymmetric geminate recasting | Nat. Chem. |
| 335 | Copper-catalysed asymmetric cross-coupling reactions tolerant of
highly reactive radicals | Nat. Chem. |
| 336 | Deaminative Giese-type reaction | Nat. Chem. |
| 337 | Dearomative syn-1,4-hydroalkylation and C(sp2)−H alkylation of arenes
controlled by chemoselective electrolysis | Nat. Chem. |
| 338 | Diastereo- and enantioselective 1,3-hydrofunctionalization of
trisubstituted alkenes by a directing relay | Nat. Chem. |
| 339 | Diastereodivergent synthesis of multi-substituted cycloalkanes | Nat. Chem. |
| 340 | Direct stereoselective C(sp3)–H alkylation of saturated heterocycles
using olefins | Nat. Chem. |
| 341 | Divergent access to E- or Z-trisubstituted medium-sized cycloalkenes
by Pd-catalysed cycloaddition | Nat. Chem. |
| 342 | Enantioconvergent radical addition of racemic alkyl halides to access
vicinal stereocentres | Nat. Chem. |
| 343 | Enantioselective photocatalytic synthesis of bicyclo[2.1.1]hexanes as
ortho-disubstituted benzene bioisosteres with improved biological
activity | Nat. Chem. |
| 344 | Enantioselective synthesis of 2-substituted bicyclo[1.1.1]pentanes via
sequential asymmetric imine addition of bicyclo[1.1.0]butanes and
skeletal editing | Nat. Chem. |
| 345 | Head–tail carboboration of multisubstituted alkenes enabled by chain
recognition | Nat. Chem. |
| 346 | High-pressure pump–probe experiments reveal the mechanism of excited-
state proton-coupled electron transfer and a shift from stepwise to
concerted pathways | Nat. Chem. |
| 347 | Isotope-dependent Tafel analysis probes proton transfer kinetics
during electrocatalytic water splitting | Nat. Chem. |
| 348 | Leveraging electron donor–acceptor complexes for kinetic resolution in
catalytic asymmetric photochemical synthesis | Nat. Chem. |
| 349 | Light-activated hypervalent iodine agents enable diverse aliphatic C–H
functionalization | Nat. Chem. |
| 350 | Light-promoted aromatic denitrative chlorination | Nat. Chem. |
| 351 | Modular alkyl growth in amines via the selective insertion of alkynes
into C–C bonds | Nat. Chem. |
| 352 | Non-enzymatic methylcyclization of alkenes | Nat. Chem. |
| 353 | Olefin π-coordination chemistry at low-oxidation-state boron | Nat. Chem. |
| 354 | On-DNA C–H functionalization of electron-rich arenes for DNA-encoded
libraries | Nat. Chem. |
| 355 | Organocatalysed three-component modular synthesis of BN isosteres and
BN-2,1-azaboranaphthalenes via Wolff-type rearrangement | Nat. Chem. |
| 356 | Preparation, separation and storage of N-monofluoromethyl amides and
carbamates | Nat. Chem. |
| 357 | Selective arylation of atypical C–F bonds in polyfluoroarenes with
aryl chlorides | Nat. Chem. |
| 358 | Small-molecule-catalysed deamination enables transcriptome-wide
profiling of N6-methyladenosine in RNA | Nat. Chem. |
| 359 | Stable single-site organonickel catalyst preferentially hydrogenolyses
branched polyolefin C–C bonds | Nat. Chem. |
| 360 | Stereoselective amino alcohol synthesis via chemoselective
electrocatalytic radical cross-couplings | Nat. Chem. |
| 361 | Switchable skeletal editing of quinolines enabled by cyclizative
sequential rearrangements | Nat. Chem. |
| 362 | Synthesis of strained, air-stable boracycles via boron–carbon-centred
diradicals | Nat. Chem. |
| 363 | Synthesis of tertiary alkyl amines via photoinduced copper-catalysed
nucleophilic substitution | Nat. Chem. |
| 364 | Triplet state reactivity of iminium ions in organocatalytic asymmetric
[2 + 2] photocycloadditions | Nat. Chem. |
| 365 | Tunable cobalt-catalysed hydrogenation of allenes enabled by multiple
metal–ligand cooperative functionalities | Nat. Chem. |
| 366 | Unlocking azole chemical space via modular and regioselective
N-alkylation | Nat. Chem. |
| 367 | Barcode-free hit discovery from massive libraries enabled by automated
small molecule structure annotation | Nat. Comm. |
| 368 | Deoxygenative photochemical alkylation of secondary amides enables a
streamlined synthesis of substituted amines | Nat. Comm. |
| 369 | Enantioselective construction of cyclic quaternary stereocenters via
dinuclear copper catalyzed asymmetric [3 + 2]
propargylation/annulation | Nat. Comm. |
| 370 | Highly parallel optimisation of chemical reactions through automation
and machine intelligence | Nat. Comm. |
| 371 | Iridium porphyrin-catalysed asymmetric carbene insertion into primary
N-adjacent C–H bonds with TON over 1000000 | Nat. Comm. |
| 372 | Protonation pathway for CO2 reduction mediated by coordinated H2O on
active sites | Nat. Comm. |
| 373 | Ring-opening functionalizations of unstrained cyclic amines enabled by
difluorocarbene transfer | Nat. Comm. |
| 374 | Electrochemical oxidation enables aromatic C–H amination with dual
mechanisms | Nat. Synth. |
| 375 | Accelerating the discovery of multicatalytic cooperativity | Nature |
| 376 | Aromatic ring-opening metathesis | Nature |
| 377 | Boron-mediated modular assembly of tetrasubstituted alkenes | Nature |
| 378 | Catalytic allylation of native hexoses and pentoses in water with
indium | Nature |
| 379 | Catalytic enantioselective synthesis of alkylidenecyclopropanes | Nature |
| 380 | Complete computational design of high-efficiency Kemp elimination
enzymes | Nature |
| 381 | Controlling pyramidal nitrogen chirality by asymmetric organocatalysis | Nature |
| 382 | Copper-dependent halogenase catalyses unactivated C−H bond
functionalization | Nature |
| 383 | De novo design of transmembrane fluorescence-activating proteins | Nature |
| 384 | De novo designed proteins neutralize lethal snake venom toxins | Nature |
| 385 | Deaminative cross-coupling of amines by boryl radical β-scission | Nature |
| 386 | Decoding the redox behaviour of copper in Ullmann-type coupling
reactions | Nature |
| 387 | Deconstruction of rubber via C–H amination and aza-Cope rearrangement | Nature |
| 388 | Degradable thermosets via orthogonal polymerizations of a single
monomer | Nature |
| 389 | Direct deaminative functionalization with N-nitroamines | Nature |
| 390 | Dynamic kinetic resolution of phosphines with chiral supporting
electrolytes | Nature |
| 391 | Electricity-driven enzymatic dynamic kinetic oxidation | Nature |
| 392 | Engineered enzymes for enantioselective nucleophilic aromatic
substitutions | Nature |
| 393 | Generalizing arene C–H alkylations by radical–radical cross-coupling | Nature |
| 394 | Modular arene functionalization by differential 1,2-diborylation | Nature |
| 395 | One-carbon homologation of alkenes | Nature |
| 396 | Photocatalytic C–F bond activation in small molecules and
polyfluoroalkyl substances | Nature |
| 397 | Photocatalytic oxygen-atom transmutation of oxetanes | Nature |
| 398 | Photochemical permutation of thiazoles, isothiazoles and other azoles | Nature |
| 399 | Photoinduced copper-catalysed deracemization of alkyl halides | Nature |
| 400 | Preparation of a neutral nitrogen allotrope hexanitrogen C2h-N6 | Nature |
| 401 | Repurposing haemoproteins for asymmetric metal-catalysed H atom
transfer | Nature |
| 402 | Scalable total synthesis of saxitoxin and related natural products | Nature |
| 403 | Selective methylene oxidation in α,β-unsaturated carbonyl natural
products | Nature |
| 404 | Stereodivergent transformation of a natural polyester to enantiopure
PHAs | Nature |
| 405 | Stereoretentive radical cross-coupling | Nature |
| 406 | Strategic atom replacement enables regiocontrol in pyrazole alkylation | Nature |
| 407 | Synthesis of deuterated acids and bases using bipolar membranes | Nature |
| 408 | Synthesis of enantioenriched atropisomers by biocatalytic
deracemization | Nature |
| 409 | Transducing chemical energy through catalysis by an artificial
molecular motor | Nature |
| 410 | β-C−H bond functionalization of ketones and esters by cationic Pd
complexes | Nature |
| 411 | σ-Bond insertion reactions of two strained diradicaloids | Nature |
| 412 | Atom-Economical and Scalable Asymmetric Synthesis of Daridorexant Key
Starting Material ( S
)-2-Methylproline via the Memory of Chirality | OPRD |
| 413 | Biocatalytic Aerobic Oxidation for Large-Scale Production of
trans-3-Hydroxy-l-Proline | OPRD |
| 414 | Comprehensive Synthetic Route Redesign of AZD5991: A High-Complexity
Atropisomeric Macrocycle | OPRD |
| 415 | Improved Synthesis for the 4-Pyridone Intermediate of Baloxavir
Marboxil: Elimination of Polar Aprotic Solvents and Optimization
Through Design of Experiments (DoE) | OPRD |
| 416 | Lessons Learned during 50 kg Manufacturing of Suzuki–Miyaura Coupling
Reaction | OPRD |
| 417 | SDMA (Synhydrid, Red-Al, Vitride): A Chemoselective and Safe Solution
for Reduction Reactions | OPRD |
| 418 | Swiping Right on Palladium: Matching Precursors, Ligands, and Reaction
Conditions | OPRD |
| 419 | A Modular Approach to Trisubstituted Chiral Piperidines | Org. Lett. |
| 420 | Catalytic Synergy Drives Triazole-Directed
ortho -C(sp
2 )–H Functionalization | Org. Lett. |
| 421 | Elucidation of a Parasitic Proton-Coupled Electron Transfer in a
Photocatalytic Benzylic C–H Sulfonamidation | Org. Lett. |
| 422 | Photoredox-Mediated C–N Bond Cleavage Enables Synthesis of
Tetra -Substituted Olefins via Reductive
Radical-Polar Crossover | Org. Lett. |
| 423 | Switchable and Ring-Selective Hydrogenation of Naphthyridine Isomers | Org. Lett. |
| 424 | A Change in C–H Activation Mechanism: Experimental and Computational
Investigations of Rh-Catalyzed Disubstituted Benzene Functionalization | Organometallics |
| 425 | Activation and Functionalization of Organic Disulfides by
Bis(Perfluoroalkyl) Complexes of Nickel(II) | Organometallics |
| 426 | Divergent Mechanisms in the Addition of (NHC)Au(I)–H and (NHC)Cu(I)–H
across Alkynes | Organometallics |
| 427 | Exploring the Potential of a Non-Phosphine Cobalt System for Alcohol
Activation: Expedition of C–C and C–N Bond Formation | Organometallics |
| 428 | Mechanism of Ligand Exchange Processes for Titanocene Complexes: A
Computational Study | Organometallics |
| 429 | Unsymmetrical Phosphinoquinoline Iron(II) Complexes with Enhanced
Thermal Stability and High Activity for Isoprene Polymerization | Organometallics |
| 430 | 1,2-Acyl transposition through photochemical skeletal rearrangement of
2,3-dihydrobenzofurans | Science |
| 431 | An anion-binding approach to enantioselective photoredox catalysis | Science |
| 432 | Artificial farnesol epoxidase enables a concise synthesis of
meroterpenoids | Science |
| 433 | Asymmetric amination of alkyl radicals with two minimally different
alkyl substituents | Science |
| 434 | Biocatalytic, asymmetric radical hydrogenation of unactivated alkenes | Science |
| 435 | Bridging the pyridine-pyridazine synthesis gap by skeletal editing | Science |
| 436 | Carbonyl-to-sulfur swap enabled by sequential double carbon-carbon
bond activation | Science |
| 437 | Catalytic remodeling of complex alkenes to oxonitriles through C=C
double bond deconstruction | Science |
| 438 | Conformational ensembles reveal the origins of serine protease
catalysis | Science |
| 439 | De novo design of porphyrin-containing proteins as efficient and
stereoselective catalysts | Science |
| 440 | Diversity-oriented photobiocatalytic synthesis via stereoselective
three-component radical coupling | Science |
| 441 | Efficient super-reducing organic photoredox catalysis with proton-
coupled electron transfer mitigated back electron transfer | Science |
| 442 | Enantioconvergent benzylic C(sp 3
)‒N coupling with a copper-substituted nonheme enzyme | Science |
| 443 | Excited-state configuration of nitroarenes enables oxidative cleavage
of aromatics over alkenes | Science |
| 444 | Fluorine-rich poly(arylene amine) membranes for the separation of
liquid aliphatic compounds | Science |
| 445 | Gallium-catalyzed recycling of silicone waste with boron trichloride
to yield key chlorosilanes | Science |
| 446 | Harnessing carbene polarity: Unified catalytic access to donor,
neutral, and acceptor carbenes | Science |
| 447 | Homogeneous-heterogeneous bifunctionality in Pd-catalyzed vinyl
acetate synthesis | Science |
| 448 | Multigas adsorption with single-site cooperativity in a metal–organic
framework | Science |
| 449 | Nickel promotes selective ethylene epoxidation on silver | Science |
| 450 | Oxidative amination by nitrogen atom insertion into carbon-carbon
double bonds | Science |
| 451 | Photo-induced chirality in a nonchiral crystal | Science |
| 452 | Skeletal editing of pyrrolidines by nitrogen-atom insertion | Science |
| 453 | Spiro-C(sp 3 )-atom transfer:
Creating rigid three-dimensional structures with Ph
2 SCN 2 | Science |
| 454 | Stereo-reversed E2 unlocks Z -selective
C–H functionalization | Science |
| 455 | Sulfenylnitrene-mediated nitrogen-atom insertion for late-stage
skeletal editing of N -heterocycles | Science |
| 456 | Sulfonyl hydrazides as a general redox-neutral platform for radical
cross-coupling | Science |
| 457 | The total synthesis of (−)-spiroaspertrione A: A divinylcyclopropane
rearrangement approach | Science |
| 458 | Trifluoromethylation of alkyl electrophiles with
11 C- or
18 F-labeled fluoroform for PET
applications | Science |
| 459 | Visible light–driven stereodivergent allylation of cyclic hemiacetals
with butene for polypropionate synthesis | Science |
| 460 | Visible light–triggered depolymerization of commercial
polymethacrylates | Science |
| 461 | Iron-Mediated Methyl Esterification with Dibromomethane | Synthesis |
| 462 | A catalytically generated transition metal analog of the Simmons–Smith
reagent | Tetrahedron |
| 463 | A reaction enumeration analysis of building blocks to target novel
coupling methods | Tett. Lett. |
| 464 | Catalytic reductive annulation reactions of alkenes using
dihaloalkanes | Tett. Lett. |